Endocrine Abstracts

Background: Severe hypertriglyceridemia (HT) increases the risk of pancreatitis, whereas mild HT may be a risk factor for cardiovascular disease. The variety of hypertriglyceridemia origins often makes the etiological diagnosis complex.Case report: A 24-year-old female G3P0Ab2 with type 1 diabetes mellitus (T1DM) was referred at 27th week of gestation to the Endocrinology Department in July 2017 for glycemic instability and severe hypertriglyceridemia. T...

Insulin autoimmune syndrome (IAS; Hirata syndrome) is a rare cause of hypoglycemia. It seems to be related to specific HLA class II alleles. Rarely, monoclonal antibody acts as an insulin-binding autoantibody: until now 10 cases have been described in association with a myeloproliferative disorder. In June 2015, a 60-year-old patient presented in a local hospital in Mayotte with confusion, sweating and severe hypoglycemia (blood glucose as low as 20 mg/dl). He was suffering of...

Background: Oncocytic neoplasms are rare adrenal tumours usually considered as benign and non-functional. Conversely, in recent large nationwide study from COMETE network over 50% of the oncocytic adrenocortical tumours were diagnosed as carcinoma according to Lin Weiss-Bisceglia-score. However, until now only 11 cases of metastatic oncocytoma were reported in English literature.Case report: A 54-year-old man with history of abdominal pain and weight los...

Background: Delayed new-onset Graves’ orbitopathy (GO) or worsening of existing GO occurs in approximately 15–20% of patients following radioiodine treatment (RAI), mostly within 12 month.Case Report: A 57-years-old woman was referred in April 2016 to our endocrinology department for Graves’ disease hyperthyroidism. Relevant medical history included chronic lymphocytic leukemia (2004), fludarabine-related interstitial pneumonia with tempor...